The increasing recognition of NMN as a supplement to slow down aging stems from lots of scientific research showing that NMN can slow down aging, and by positive claims about NMN as a longevity ingredient by well-known researchers, like Professor David Sinclair from Harvard University, Professor Shin-ichiro Imai from Washington University, and many other folks (R,R,R,R,R).
So now you can buy NMN supplements everywhere.
However, this drastically elevated demand lead also to unscrupulous sellers to provide low-purity NMN supplements, or even NMN supplements that do not contain NMN.
Troubles with NMN supplements
Some NMN supplements claim to be “high-purity NMN,” when they are in truth low-purity NMN. Some NMN supplements even have significantly less than 80 percent purity.
Also, what the other 20 % contains is not identified to consumers. It can be just fillers like flour (utilised to minimize the price), or it could be toxic substances made as a by-product from the NMN production method.
There are even “NMN supplements” that do not include NMN, but rather include nicotinamide (a B vitamin that appears somewhat like NMN but has complete different effects in the physique), or that contain nicotinamide riboside (NR).
NR is not the similar as NMN. There are several reasons to believe that NMN is better than NR. We clarify in this weblog post why.
Provided the incredibly high manufacturing costs of NMN (it’s one particular of the most costly food supplements to produce) some NMN supplement sellers adulterate their products to cut down the charges and make more profit.
How to uncover the best NMN supplement?
So how can you obtain the best NMN supplement? And make sure nmn 免疫 is a trustworthy, fantastic excellent one?
You would have to have to pay focus to the following points:
1. The NMN organization has esteemed scientific advisors
Make sure your NMN supplement is from a firm that has major longevity scientists in its advisory board, and operates with scientific consultants that are popular in the field of aging.
You can google these researchers to see if they are connected to a university or lab, and check on PubMed how several studies they have published.
That way you can make sure they are active, nicely-reliable scientists. We at NOVOS have such top experts as board members and advisors.
two. Be skeptical of “high-purity” NMN claims
Acquire a high-purity (containing far more than 99 % NMN) supplement, so not 1 that has been adulterated with other substances.
However, be skeptical of so called “99 % purity” NMN supplements. Typically, the purity is measured subjectively, and not in an absolute way.
Usually, the “purity” is measured by comparing the supplement with other supplements that are much less pure. In this way a single can claim quite high “purities”.
Nonetheless, to establish the true purity, one particular requirements to calculate the purity in an objective manner, by measuring the absolute purity of the supplement itself.
Or, when measuring relative purity by comparing NMN with a gold regular of NMN, the brand’s purity must be much more than one hundred percent pure (e.g. 101 % purity). This signifies the NMN is much more pure than the gold normal.
3. Make sure it is stable, new-generation NMN
Did you know that not al NMN is the same?
Newer generation NMN is much more stable. NMN is a fragile molecule that when exposed to water molecules can get converted into nicotinamide (NAM).
The stability of NMN is largely determined by the surrounding water molecules, and the organization of the NMN with other surrounding NMN molecules. The water molecules are polar (having different electric charges on distinctive sides), which can effect the electron configuration of the NMN molecule and lead to significantly less stability.
NMN molecules that are much more orderly organized and extra compactly arranged suffer significantly less from the destabilizing interaction with water molecules both in the product and with water from air. In addition, creating additional “high-density” NMN by decreasing water content material improves stability.
We at NOVOS supply this type of subsequent-generation, far more steady NMN.
The NMN in NOVOS Increase arranges itself into spherical crystals (as opposed to sawtooth crystals), which are additional capable of blocking make contact with with humidity in the air, which increases the stability and shelf life of our NMN. Compared to sawtooth crystal shapes, the spherical crystal is much more ordered, compact and therefore each and every NMN molecule will have less exposure to air and water.
There exists even much more crystalline NMN (and NMN derivatives), which entails certain organization of the NMN molecules, for which David Sinclair’s enterprise MetroBiotech has filed patents. See for example this patent. On the other hand, this is likely overkill.
four. Third celebration-lab testing of NMN
Make sure NMN supplement seller has worked collectively with third party labs that checked the supplement for contaminants such as:
Heavy metals (e.g. lead, arsenic, cadmium and mercury)
Bacteria (e.g. E coli, S aureus, Salmonella)
Yeast and mold
Toxins (e.g. toluene, xylenes, trichloroethylene, isopropyl alcohol, ethylene oxide, ethyl ether, acetone, benzene, chloroform, acetonitrile, and so on). Toluene is an critical contaminant that demands to checked.
Be conscious, some providers only test heavy metals, but not microorganisms like yeast and bacteria, or only test for microorganisms and not for heavy metals.
Make sure your NMN supplement has been third-party tested by independent testing services to confirm purity and security. Many sellers of NMN supplements use much less nicely-identified and much less reputed testing firms.
5. The NMN is properly manufactured
Make positive your NMN supplement is made in a facility that performs according to GMP (Great Manufacturing Practices) and to the most recent ISO norms.
Also, the production method of NMN requirements to be state-of-the-art.
This implies for example that the pH and water content material in the course of the production procedure have to be incredibly properly controlled. A too acid or as well alkaline atmosphere will break the electric balance of the NMN crystals. NOVOS Boost NMN is pH balanced, which improves the internal structure and stability of the crystals throughout production. Additional, the water content in the crystals is controlled in the course of production, which further improves the NMN’s stability.
It is critical to use in this course of action novel-generation NMN made of spherical crystals, which has greater bulk density and fluidity, avoiding unstable dosages due to raising dust in the production course of action.
Why NOVOS’ NMN is different
NOVOS Enhance is a unique NMN supplement adhering to all of the above.
We use rigorous science, work together with the top scientific professionals in the aging field, do due diligence and conduct trustworthy extensive testing to make sure you have the best high-quality NMN supplement, which pairs excellently with our foundational formulation, NOVOS Core.
Also, our NMN is next-generation NMN that is extra stable.
NOVOS’ NMN is third-celebration tested, higher-purity NMN. Our NMN is most likely the most completely tested NMN on the marketplace: We test for far a lot more contaminants than many other providers do.